Indian trial tests olanzapine as steroid-free option for chemo vomiting in children

An Indian multicentre clinical trial suggests olanzapine may be an alternative to dexamethasone for preventing nausea and vomiting in children receiving highly emetogenic chemotherapy. Dexamethasone, a corticosteroid, is the standard guideline drug but can cause its own side effects. Researchers sought a comparable non-steroid option, since controlling vomiting helps young cancer patients complete treatment and improves their quality of life.